靶标:
AATK
产品别名:
AATYK; AATYK1; LMR1; LMTK1; PPP1R77; p35BP; AATK; apoptosis associated tyrosine kinase; apoptosis associated tyrosine kinase; serine/threonine-protein kinase LMTK1; CDK5-binding protein; brain apoptosis-associated tyrosine kinase; lemur tyrosine kinase 1; p35-binding protein; protein phosphatase 1, regulatory subunit 77; AATK细胞凋亡关联酪氨酸激酶; 凋亡关联酪氨酸激酶(AATK);
背景信息:
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],