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死亡因子4样蛋白2抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Anti-MORF4L2
Anti-mortality factor 4 like 2 Antibody
靶标:

MORF4L2


产品别名:

MORFL2; MRGX; MORF4L2; mortality factor 4 like 2; mortality factor 4 like 2; mortality factor 4-like protein 2; MORF-related gene X protein; MSL3-2 protein; protein MSL3-2; transcription factor-like protein MRGX; 死亡因子4样蛋白2;


背景信息:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
 
 
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