钙调蛋白依赖性蛋白激酶磷酸酶抗体

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钙调蛋白依赖性蛋白激酶磷酸酶抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Anti-PPM1F
Anti-protein phosphatase, Mg2+/Mn2+ dependent 1F Antibody

靶标：

PPM1F

产品别名：

CAMKP； CaMKPase； FEM-2； POPX2； hFEM-2； PPM1F； protein phosphatase, Mg2+/Mn2+ dependent 1F； protein phosphatase, Mg2+/Mn2+ dependent 1F； protein phosphatase 1F； Ca(2+)/calmodulin-dependent protein kinase phosphatase； CaM-kinase phosphatase； PP2C phosphatase； partner of PIX 2； protein fem-2 homolog； protein phosphatase 1F (PP2C domain containing)；钙调蛋白依赖性蛋白激酶磷酸酶；

背景信息：

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。