靶标:
DZIP3
产品别名:
PPP1R66; UURF2; hRUL138; DZIP3; DAZ interacting zinc finger protein 3; DAZ interacting zinc finger protein 3; E3 ubiquitin-protein ligase DZIP3; DAZ interacting protein 3, zinc finger; DAZ-interacting protein 3; RING-type E3 ubiquitin transferase DZIP3; RNA-binding RING-H2 protein-ubiquitin ligase; RNA-binding ubiquitin ligase of 138 kDa; UURF2 ubiquitin ligase; human RNA-binding ubiquitin ligase of 138 kDa; protein phosphatase 1, regulatory subunit 66; zinc finger DAZ interacting protein 3; E3泛素蛋白连接酶dzip3; RNA结合泛素连接酶DZIP3;
背景信息:
function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.,pathway:Protein modification; protein ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with DAZ proteins.,tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.,