靶标:
CLINT1
产品别名:
CLINT; ENTH; EPN4; EPNR; CLINT1; clathrin interactor 1; clathrin interactor 1; clathrin interactor 1; clathrin interacting protein localized in the trans-Golgi region; enthoprotin; epsin 4; epsin-related protein; epsinR;
背景信息:
This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.