靶标：
DOCK4
产品别名：
DOCK4； dedicator of cytokinesis 4； dedicator of cytokinesis 4； dedicator of cytokinesis protein 4； 细胞质分裂付出蛋白4； 胞质分裂作用因子4(DOCK4)；
背景信息：
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008],
