靶标:
SART3
产品别名:
DSAP1; P100; RP11-13G14; TIP110; p110; p110(nrb); SART3; spliceosome associated factor 3, U4/U6 recycling protein; spliceosome associated factor 3, U4/U6 recycling protein; squamous cell carcinoma antigen recognized by T-cells 3; HIV-1 Tat-interacting protein of 110kDa; PRP24 homolog; SART-3; hSART-3; p110 nuclear RNA-binding protein; squamous cell carcinoma antigen recognized by T cells 3; tat-interacting protein of 110 kDa; T淋巴细胞识别的鳞状细胞癌SART3;
背景信息:
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008],