靶标:
BCLAF1
产品别名:
BTF; bK211L9.1; BCLAF1; BCL2 associated transcription factor 1; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCLAF1 and THRAP3 family member 1; Bcl2相关转录因子;
背景信息:
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],