靶标:
MRC2
产品别名:
CD280; CLEC13E; ENDO180; UPARAP; MRC2; mannose receptor C type 2; mannose receptor C type 2; C-type mannose receptor 2; C-type lectin domain family 13 member E; UPAR-associated protein; endocytic receptor (macrophage mannose receptor family); endocytic receptor 180; macrophage mannose receptor 2; urokinase-type plasminogen activator receptor-associated protein; 巨噬细胞甘露糖受体2; 甘露糖受体C2(MRC2);
背景信息:
mannose receptor C type 2(MRC2) Homo sapiens This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012],