靶标:
MVP
产品别名:
LRP; VAULT1; MVP; major vault protein; major vault protein; major vault protein; lung resistance-related protein; testicular secretory protein Li 30; 主要穹窿蛋白(MVP); 肺耐药相关蛋白;
背景信息:
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012],