靶标：
SH2B3
产品别名：
IDDM20； LNK； SH2B3； SH2B adaptor protein 3； SH2B adaptor protein 3； SH2B adapter protein 3； lymphocyte-specific adapter protein Lnk； signal transduction protein Lnk； 淋巴细胞特异性接头蛋白； 淋巴细胞衔接蛋白(Lnk)；
背景信息：
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
