靶标:
DNAJB6
产品别名:
DJ4; DnaJ; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; LGMDD1; MRJ; MSJ-1; DNAJB6; DnaJ heat shock protein family (Hsp40) member B6; DnaJ heat shock protein family (Hsp40) member B6; dnaJ homolog subfamily B member 6; DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ-like 2 protein; heat shock protein J2; 热休克蛋白J2;
背景信息:
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008],