靶标：
ABCB6
产品别名：
ABC； LAN； MTABC3； PRP； umat； ABCB6； ATP binding cassette subfamily B member 6 (Langereis blood group)； ATP binding cassette subfamily B member 6 (Langereis blood group)； ATP-binding cassette sub-family B member 6； ABC-type heme transporter ABCB6； ATP-binding cassette half-transporter； ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)； P-glycoprotein-related protein； mitochondrial ABC transporter 3； mt-ABC transporter 3； ubiquitously-expressed mammalian ABC half transporter； ATP结合盒转运蛋白B6(ABCB6)； ATP结合蛋白家族6；
背景信息：
ABCB6, ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
