靶标:
DPP3
产品别名:
DPPIII; DPP3; dipeptidyl peptidase 3; dipeptidyl peptidase 3; dipeptidyl peptidase 3; DPP III; dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; dipeptidyl peptidase III; enkephalinase B; 二肽基肽酶3(DPP3); 二肽氨基肽酶3;
背景信息:
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.