靶标:
CERT1
产品别名:
CERT; CERTL; COL4A3BP; GPBP; MRD34; STARD11; CERT1; ceramide transporter 1; ceramide transporter 1; ceramide transfer protein; StAR-related lipid transfer (START) domain containing 11; collagen type IV alpha 3 binding protein; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; lipid-transfer protein CERTL; IV型胶原α3结合蛋白;
背景信息:
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.