靶标:
ACTR1B
产品别名:
ARP1B; CTRN2; PC3; ACTR1B; actin related protein 1B; actin related protein 1B; beta-centractin; ARP1 actin related protein 1 homolog B; ARP1 actin-related protein 1 homolog B, centractin beta; centractin beta; 中心体肌动蛋白β(CTRN2); 肌动蛋白相关蛋白1B;
背景信息:
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],