靶标:
ZNF263
产品别名:
FPM315; ZKSCAN12; ZSCAN44; ZNF263; zinc finger protein 263; zinc finger protein 263; zinc finger protein 263; zinc finger protein FPM315; zinc finger protein with KRAB and SCAN domains 12; 锌指蛋白263;
背景信息:
Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions.