靶标:
GDF11
产品别名:
BMP-11; BMP11; VHO; GDF11; growth differentiation factor 11; growth differentiation factor 11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11; 生长分化因子11(GDF11); 骨形态发生蛋白11;
背景信息:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016],