靶标：
RCAN2
产品别名：
CSP2； DSCR1L1； MCIP2； RCN2； ZAKI-4； ZAKI4； RCAN2； regulator of calcineurin 2； regulator of calcineurin 2； calcipressin-2； Down syndrome candidate region 1-like 1； Down syndrome critical region gene 1-like 1； myocyte-enriched calcineurin-interacting protein 2； thyroid hormone-responsive (skin fibroblasts)； thyroid hormone-responsive protein ZAKI-4； 钙加压素2；
背景信息：
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
