靶标:
RIDA
产品别名:
HRSP12; P14.5; PSP; UK114; hp14.5; RIDA; reactive intermediate imine deaminase A homolog; reactive intermediate imine deaminase A homolog; 2-iminobutanoate/2-iminopropanoate deaminase; 14.5 kDa translational inhibitor protein; UK114 antigen homolog; heat-responsive protein 12; perchloric acid-soluble protein; ribonuclease UK114; translation inhibitor L-PSP ribonuclease; translational inhibitor p14.5; translational inhibitor protein p14.5; 热反应蛋白12;
背景信息:
Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase. May also function as an endoribonuclease, cleaving mRNA phosphodiester bonds of single-stranded RNA (By similarity). Thereby, may inhibit protein translation (PubMed:8973653).