靶标：
ZMPSTE24
产品别名：
FACE-1； FACE1； HGPS； PRO1； RSDM1； STE24； Ste24p； ZMPSTE24； zinc metallopeptidase STE24； zinc metallopeptidase STE24； CAAX prenyl protease 1 homolog； farnesylated proteins-converting enzyme 1； prenyl protein-specific endoprotease 1； zinc metallopeptidase STE24 homolog； zinc metalloproteinase Ste24 homolog； 锌金属蛋白酶STE24同源蛋白；
背景信息：
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
