靶标:
TRAIP
产品别名:
RNF206; SCKL9; TRIP; TRAIP; TRAF interacting protein; TRAF interacting protein; E3 ubiquitin-protein ligase TRAIP; RING-type E3 ubiquitin transferase TRAIP; ring finger protein 206; 肿瘤坏死因子受体相互作用蛋白;
背景信息:
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008],