靶标:
SIRPB1
产品别名:
CD172b; SIRP-BETA-1; SIRPB1; signal regulatory protein beta 1; signal regulatory protein beta 1; signal-regulatory protein beta-1; CD172 antigen-like family member B; 信号调节蛋白β1(SIRPb1); 信号调节蛋白β1/SIRP-ß1;
背景信息:
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],