靶标:
ABCA9
产品别名:
EST640918; ABCA9; ATP binding cassette subfamily A member 9; ATP binding cassette subfamily A member 9; ATP-binding cassette sub-family A member 9; ATP-binding cassette A9; ATP-binding cassette, sub-family A (ABC1), member 9; ATP结合盒转运蛋白A9(ABCA9); 三磷酸腺苷结合盒转运蛋白9;
背景信息:
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008],