靶标:
WARS2
产品别名:
NEMMLAS; PKDYS3; TrpRS; mtTrpRS; WARS2; tryptophanyl tRNA synthetase 2, mitochondrial; tryptophanyl tRNA synthetase 2, mitochondrial; tryptophan--tRNA ligase, mitochondrial; (Mt)TrpRS; tryptophan tRNA ligase 2, mitochondrial; 色氨酰tRNA合成酶2(WARS2);
背景信息:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],