靶标:
CD2BP2
产品别名:
FWP010; LIN1; PPP1R59; Snu40; U5-52K; CD2BP2; CD2 cytoplasmic tail binding protein 2; CD2 cytoplasmic tail binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; U5 snRNP 52K protein; protein phosphatase 1, regulatory subunit 59;
背景信息:
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],