靶标:
UBAC1
产品别名:
GBDR1; KPC2; UBADC1; UBAC1; UBA domain containing 1; UBA domain containing 1; ubiquitin-associated domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; Kip1 ubiquitination-promoting complex subunit 2; UBA domain-containing protein 1; glialblastoma cell differentiation-related protein 1; kip1 ubiquitination-promoting complex protein 2; putative glialblastoma cell differentiation-related protein; testicular secretory protein Li 64; ubiquitin associated domain containing 1; E3泛素蛋白连接酶亚基KPC2;
背景信息:
function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,