靶标：
UBE2E3
产品别名：
UBCH9； UbcM2； UBE2E3； ubiquitin conjugating enzyme E2 E3； ubiquitin conjugating enzyme E2 E3； ubiquitin-conjugating enzyme E2 E3； E2 ubiquitin-conjugating enzyme E3； ubiquitin carrier protein E3； ubiquitin conjugating enzyme E2E 3； ubiquitin-conjugating enzyme E2-23 kDa； ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)； ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5)； ubiquitin-protein ligase E3； 泛素蛋白连接酶E3；
背景信息：
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013],
