靶标:
CCT4
产品别名:
CCT-DELTA; Cctd; SRB; CCT4; chaperonin containing TCP1 subunit 4; chaperonin containing TCP1 subunit 4; T-complex protein 1 subunit delta; TCP-1-delta; chaperonin containing TCP1, subunit 4 (delta); chaperonin containing t-complex polypeptide 1, delta subunit; stimulator of TAR RNA-binding;
背景信息:
T-complex protein 1 subunit delta is a protein that in humans is encoded by the CCT4 gene. This gene is mapped to 2p15. The chaperonin containing TCP1 complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin and tubulin, as well as alpha-transducin.