靶标:
TRIM3
产品别名:
BERP; HAC1; RNF22; RNF97; TRIM3; tripartite motif containing 3; tripartite motif containing 3; tripartite motif-containing protein 3; RING finger protein 97; brain expressed ring finger; brain-expressed RING finger protein; ring finger protein 22; tripartite motif protein TRIM3; 含三联基元蛋白3(TRIM3); 环指蛋白22;
背景信息:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008],