靶标：
MASP2
产品别名：
MAP-2； MAP19； MASP-2； MASP1P1； sMAP； MASP2； MBL associated serine protease 2； MBL associated serine protease 2； mannan-binding lectin serine protease 2； MBL-associated plasma protein of 19 kD； mannan binding lectin serine peptidase 2； mannan-binding lectin serine peptidase 1 pseudogene 1； mannan-binding lectin serine protease 1 pseudogene 1； mannose-binding lectin associated protein 19； mannose-binding lectin-associated serine protease 2； mannose-binding protein-associated serine protease 2； small MBL-associated protein； 甘露聚糖结合凝集素丝氨酸肽酶2； 甘露聚糖结合凝集素关联丝氨酸蛋白酶2(MASP2)；
背景信息：
mannan binding lectin serine peptidase 2(MASP2) Homo sapiens This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],
