靶标:
HSPH1
产品别名:
HSP105; HSP105A; HSP105B; NY-CO-25; HSPH1; heat shock protein family H (Hsp110) member 1; heat shock protein family H (Hsp110) member 1; heat shock protein 105 kDa; antigen NY-CO-25; heat shock 105kDa/110kDa protein 1; 105kDa/110kDa热休克蛋白1(HSPH1); 热休克蛋白105;
背景信息:
function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,