靶标:
PDE10A
产品别名:
ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19; PDE10A; phosphodiesterase 10A; phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; 3',5' cAMP/cGMP phosphodiesterase; dJ416F21.1 (phosphodiesterase 10A); phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7); 磷酸二酯酶10A; 磷酸二酯酶10A(PDE10A);
背景信息:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],