靶标:
CCL27
产品别名:
ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27; CCL27; C-C motif chemokine ligand 27; C-C motif chemokine ligand 27; C-C motif chemokine 27; CC chemokine ILC; IL-11 R-alpha-locus chemokine; IL-11 Ralpha-locus chemokine; chemokine (C-C motif) ligand 27; cutaneous T-cell attracting chemokine; skinkine; small inducible cytokine subfamily A (Cys-Cys), member 27; small-inducible cytokine A27; 皮肤T细胞虏获趋化因子; 趋化因子配体27(CCL27);
背景信息:
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.