靶标：
LILRB5
产品别名：
CD85C； LIR-8； LIR8； LILRB5； leukocyte immunoglobulin like receptor B5； leukocyte immunoglobulin like receptor B5； leukocyte immunoglobulin-like receptor subfamily B member 5； CD85 antigen-like family member C； leucocyte Ig-like receptor B5； leukocyte immunoglobulin-like receptor 8； leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5； 白细胞免疫球蛋白样受体8；
背景信息：
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
