靶标:
TLK2
产品别名:
HsHPK; MRD57; PKU-ALPHA; TLK2; tousled like kinase 2; tousled like kinase 2; serine/threonine-protein kinase tousled-like 2; 丝氨酸/苏氨酸激酶TLK2;
背景信息:
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],