靶标：
DNAJB4
产品别名：
DNAJW； DjB4； HLJ1； DNAJB4； DnaJ heat shock protein family (Hsp40) member B4； DnaJ heat shock protein family (Hsp40) member B4； dnaJ homolog subfamily B member 4； DnaJ (Hsp40) homolog, subfamily B, member 4； DnaJ-like heat shock protein 40； HSP40 homolog； heat shock 40 kDa protein 1 homolog； heat shock protein 40 homolog； human liver DnaJ-like protein；
背景信息：
The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
