靶标：
ADAMTS8
产品别名：
ADAM-TS8； METH2； ADAMTS8； ADAM metallopeptidase with thrombospondin type 1 motif 8； ADAM metallopeptidase with thrombospondin type 1 motif 8； A disintegrin and metalloproteinase with thrombospondin motifs 8； ADAMTS-8； METH-2； METH-8； a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8； 整合素样金属蛋白酶与凝血酶8型； 血小板反应蛋白解整合素金属肽酶8(ADAMTS8)；
背景信息：
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.
