靶标:
SLC7A9
产品别名:
BAT1; CSNU3; SLC7A9; solute carrier family 7 member 9; solute carrier family 7 member 9; B(0,+)-type amino acid transporter 1; b(0,+)AT; glycoprotein-associated amino acid transporter b0,+AT1; solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9; solute carrier family 7 (cationic amino acid transporter, y+ system), member 9; solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9; 溶质载体家族7成员9(SLC7A9); 离子转运相关蛋白SLC7A9;
背景信息:
b(0,+)-type amino acid transporter 1, also known as b(0,+)AT1, is a protein which in humans is encoded by the SLC7A9 gene. This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids, and appears to function in the reabsorption of cystine in the kidney tubule. Mutations in this gene cause non-type I cystinuria, a disease that leads to cystine stones in the urinary system due to impaired transport of cystine and dibasic amino acids. Alternate transcript variants, which encode the same protein, have been found for this gene.