靶标：
MAP4K5
产品别名：
GCKR； KHS； KHS1； MAPKKKK5； MAP4K5； mitogen-activated protein kinase kinase kinase kinase 5； mitogen-activated protein kinase kinase kinase kinase 5； mitogen-activated protein kinase kinase kinase kinase 5； MAPK/ERK kinase kinase kinase 5； MEK kinase kinase 5； MEKKK 5； germinal center kinase-related； kinase homologous to SPS1/STE20； 丝裂原激活蛋白激酶激酶激酶激酶5(MAP4K5)；
背景信息：
mitogen-activated protein kinase kinase kinase kinase 5(MAP4K5) Homo sapiens This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],
