靶标：
RASSF8
产品别名：
C12orf2； HOJ1； RASSF8； Ras association domain family member 8； Ras association domain family member 8； ras association domain-containing protein 8； Ras association (RalGDS/AF-6) domain family (N-terminal) member 8； carcinoma-associated protein HOJ-1； RAS家族关联结构域蛋白8；
背景信息：
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],
