靶标：
B4GALT7
产品别名：
EDSP1； EDSSLA； EDSSPD1； XGALT1； XGPT； XGPT1； B4GALT7； beta-1,4-galactosyltransferase 7； beta-1,4-galactosyltransferase 7； beta-1,4-galactosyltransferase 7； UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7； UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7； UDP-galactose:beta-xylose beta-1,4-galactosyltransferase； beta-1,4-GalTase 7； beta-1,4-galactosyltransferase VII； beta4Gal-T7； beta4GalT-VII； galactosyltransferase I； proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I； xylosylprotein 4-beta-galactosyltransferase； xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7； xylosylprotein beta-1,4-galactosyltransferase； 半乳糖转移酶7亚基β1,4；
背景信息：
This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. M
