靶标：
Bex3
产品别名：
AL033356； DXWsu67e； Gcap27； Nade； Ngfrap1； Bex3； brain expressed X-linked 3； brain expressed X-linked 3； protein BEX3； brain-expressed X-linked protein 3 homolog； granule cell antiserum positive 27； nerve growth factor receptor (TNFRSF16) associated protein 1； nerve growth factor receptor-associated protein 1； p75NTR-associated Cell Death Executor； 神经生长因子受体相关蛋白1；
背景信息：
domain:The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.,function:May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.,miscellaneous:Binds transition metals.,PTM:Ubiquitinated. Degraded by the proteasome.,similarity:Belongs to the BEX family.,subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.,subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC (By similarity). Binds to the DEATH domain of p75NTR/NGFR.,tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.,
