靶标:
Bglap2
产品别名:
BGP2; Bglap1; Bgp; Og2; mOC-B; Bglap2; bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamate protein 2; osteocalcin-2; bone Gla protein 2; gamma-carboxyglutamic acid-containing protein 2; osteocalcin; 骨钙素(OC);
背景信息:
Osteocalcin belongs to the osteocalcin matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.