靶标:
Bmp8a
产品别名:
Bmp7r1; OP-2; OP2; Bmp8a; bone morphogenetic protein 8a; bone morphogenetic protein 8a; bone morphogenetic protein 8A; osteogenic protein 2; 骨形成蛋白8A(BMP8A);
背景信息:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],