靶标:
Eps15l1
产品别名:
9830147J04Rik; AI593686; Eps15-rs; Eps15R; Eps15l1; epidermal growth factor receptor pathway substrate 15-like 1; epidermal growth factor receptor pathway substrate 15-like 1; epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor pathway substrate 15-related sequence; eps15-related protein; 表皮生长因子受体底物15;
背景信息:
function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,