靶标:
Sfxn1
产品别名:
2810002O05Rik; A930015P12Rik; Sfxn1; sideroflexin 1; sideroflexin 1; sideroflexin-1; flexed tail; Sideroflexin 1蛋白(SFXN1); 三羧酸载体蛋白SFXN1;
背景信息:
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Transports both D-serine and L-serine. Also able to transport other amino-acids, such as alanine. May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity.