靶标：
Hey2
产品别名：
CHF1； Herp1； Hrt2； bHLHb32； hesr2； Hey2； hairy/enhancer-of-split related with YRPW motif 2； hairy/enhancer-of-split related with YRPW motif 2； hairy/enhancer-of-split related with YRPW motif protein 2； HES-related repressor protein 2； HESR-2； HRT-2； Hairy-E(spl)-related with YRPW motif 2； hairy and enhancer of split related 2； hairy and enhancer of split-related protein 2； hairy-related transcription factor 2； mHRT2； protein gridlock homolog； 转录因子HEY2蛋白；
背景信息：
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
