靶标：
Invs
产品别名：
Nphp2； inv； Invs； inversin； inversin； inversin； inversion of embryo turning protein； nephrocystin 2； 内脏器官发育转位相关蛋白NPH2； 肾结核蛋白2(NPHP2)；
背景信息：
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012],
