靶标:
Mdfic
产品别名:
Kdt1; Mdfid; Mdfic; MyoD family inhibitor domain containing; MyoD family inhibitor domain containing; myoD family inhibitor domain-containing protein; I-mfa domain-containing protein; kidney cell line-derived transcript 1; 肌原调节抑制蛋白;
背景信息:
This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],